sexta-feira, 11 de agosto de 2017

CRISPR usado para criar porcos livres de PERV

... que pode ser transmitido a humanos (se órgãos transplantados em humanos):
https://www.usatoday.com/story/news/nation-now/2017/08/11/scientists-closer-using-pig-organs-humans-working-pig-2-0/55903800

Citando:
"The company and its collaborators published their work in the journal Science, where they explain how they created the PERV-less piglets.

Using a genome-editing tool named CRISPR, the researchers created PERV-free embryos, implanted them into surrogate female pigs, which gave birth to piglets without the retrovirus. 

The piglets are now four-and-a-half months old and will be monitored for any long-term effects. "

(...)
"But the fear of transmitting PERVs to humans was, among other hurdles, blocking progress toward successful xenotransplantation, making the eGenesis find an important one."