domingo, 24 de março de 2019

Sobre a resistência aos antibióticos

https://www.theguardian.com/global/2019/mar/24/the-drugs-dont-work-what-happens-after-antibiotics

Citando:
"Antimicrobial resistance (AMR) – the process of bacteria (and yeasts and viruses) evolving defence mechanisms against the drugs we use to treat them – is progressing so quickly that the UN has called it a “global health emergency”. At least 2 million Americans contract drug-resistant infections every year. So-called “superbugs” spread rapidly, in part because some bacteria are able to borrow resistance genes from neighbouring species via a process called horizontal gene transfer. In 2013, researchers in China discovered E coli containing mcr-1, a gene resistant to colistin, a last-line antibiotic that, until recently, was considered too toxic for human use. Colistin-resistant infections have now been detected in at least 30 countries."
(...)
"Making a dent in antibiotic resistance will require such international efforts. Some 90% of forecast deaths from AMR will take place in Africa and Asia – the countries where antibiotic overuse, and resistant infections, are highest. When the AMR review was published in 2016, O’Neill was encouraged by the international response. But since then, Brexit and the Trump administration have knocked AMR off the news agenda. And despite enthusiastic rhetoric, pharmaceutical companies continue to tread water.

“I occasionally think that pharmaceutical company CEOs say to themselves, ‘We’ll just wait until it becomes a real crisis,’” says O’Neill."