Sobre o circuito do medicamento (Tese)

... E como a indústria farmacêutica está sob pressão (fim de patentes e aumento de custos de I&D devido a legislação cada vez mais exigente):
http://bdigital.ufp.pt/bitstream/10284/2441/3/TM_16438.pdf

Sobre o chá verde: super-alimento ou balela?

http://www.nhs.uk/Livewell/superfoods/Pages/is-green-tea-a-superfood.aspx


PS. Resumindo, já houve alguns estudos e apenas o de protecção dos dentes tem resultados interessantes. Isto não quer dizer que o chá verde e as suas potenciais boas propriedades são uma balela (até porque seria uma balela com milhares de anos). Apenas pode querer dizer que não foram ainda feitos estudos suficientes ou os estudos certos. Os estudos custam dinheiro e é preciso que alguém esteja disposto a pagar por eles (e quem normalmente os paga quer retorno do investimento)...


(2016-06-30, act. PS)

Sobre o chá verde: super-alimento ou balela?

http://www.nhs.uk/Livewell/superfoods/Pages/is-green-tea-a-superfood.aspx

Tratamentos possíveis: NHS Choices (e hiperplasia benigna da próstata)

O sítio NHS Choices apresenta de uma forma bastante sistemática e resumida as principais alternativas para tratamento de uma série problemas de saúde. Exemplos para a hiperplasia benigna da próstata (em que a próstata aumenta de tamanho afectando órgãos ao lado - comum em homens à medida que envelhecem):
http://www.nhs.uk/Conditions/Prostate-enlargement/Pages/treatmentoptions.aspx

RESOURCE: NHS Choices Web Site (e o risco de cancro de quem bebe moderadamente)

O sítio NHS Choices (do SNS do RU) é um excelente recurso para aceder à fonte e interpretar algumas notícias sobre saúde que vão aparecendo:
http://www.nhs.uk/News/Pages/NewsIndex.aspx?TopicId=&Page=4 (Behind the headlines)
http://www.nhs.uk/pages/home.aspx (Home)


Por exemplo sobre as notícias do álcool contribuir sempre (mesmo quando ingerido moderadamente) para o cancro da mama eis a análise:
http://www.nhs.uk/news/2015/08August/Pages/Just-one-drink-a-day-may-raise-breast-cancer-risk.aspx


No final desta última ligação, ligações para as notícias (links to the headlines) e para a parte científica (links to the science).

Os números chocantes da saúde nos EUA

https://www.washingtonpost.com/news/wonk/wp/2013/03/26/21-graphs-that-show-americas-health-care-prices-are-ludicrous/?tid=pm_business_pop_b

Superbugs a chegar aos EUA (Colistin)

Mais uma notícia:


Citando:
"The mcr-1 gene makes bacteria resistant to colistin, an antibiotic used to treat multi-drug-resistant infections, including carbapenem-resistant Enterobacteriaceae or CRE, which US health officials have dubbed a 'nightmare' bacteria.
Colistin is the last antibiotic used to combat bacteria that are resistant to the strongest antibiotics."

Os vários tipos de ressono...

... E algumas acções de mitigação. Umas simples, outras nem por isso (intervenções cirúrgicas):
http://www.dailymail.co.uk/health/article-3661837/What-type-snorer-test-reveal-solutions-likely-silence-you.html

O que acontece quando um mosquito nos pica

... E como evitar que os vírus se propaguem:
http://www.ibtimes.co.uk/itchy-mosquito-bite-inflammation-enhances-replication-viruses-1566738


Citando:
"When mosquitoes bite, they probe the skin and inject saliva, causing an inflammation and triggering an immune response. White blood cells called neutrophils and myeloid cells rush to the site of the bite, but the researchers show that instead of helping, these cells in fact get infected and inadvertently replicate the virus."
(...)
"Potential treatment
These findings suggest that anti-inflammatory drugs and creams could be an interesting therapeutic option to limit the spread of the virus. They could potentially target the inflammation before the immune cells rush to the site of the bite and become infected by the virus. This could an important step in fighting viral diseases (...)"

Forma como cancro se propaga melhor compreendida (metástases)

http://www.express.co.uk/life-style/health/682809/Medical-breakthrough-Scientists-understanding-cancer-spreads

Brócolos ou não brócolos? | Behind the Headlines - NHS

Mais um interessante artigo sobre certas notícias que aparecem na comunicação social:
http://www.nhs.uk/news/2016/06June/Pages/Broccoli-compounds-may-help-combat-chronic-diseases.aspx


Citando (ler até "but" s.f.f.):
"Eating broccoli could lower your risk of having coronary heart disease, type 2 diabetes and several types of cancer, a new study suggests," the Daily Mail reports.
But there is little hard evidence to back up this claim – the study it reports on involved plants, not humans."

Brócolos ou não brócolos? | Behind the Headlines - NHS

Mais um interessante artigo sobre certas notícias que aparecem na comunicação social:
http://www.nhs.uk/news/2016/06June/Pages/Broccoli-compounds-may-help-combat-chronic-diseases.aspx


Citando (ler até "but" s.f.f.):
"Eating broccoli could lower your risk of having coronary heart disease, type 2 diabetes and several types of cancer, a new study suggests," the Daily Mail reports.
But there is little hard evidence to back up this claim – the study it reports on involved plants, not humans."

O poder da Internet?

Quando a internet encontra o que os médicos não encontram:
http://www.express.co.uk/news/uk/683304/How-I-used-Google-to-find-cancer-missed-by-doctors-nine-times

Informação sobre ciclos do sono em jovens e adolescentes (e horas de exames)

Horas de exames nacionais questionadas:
https://www.publico.pt/sociedade/noticia/o-horario-dos-exames-esta-desajustado-dos-ciclos-do-sono-1736118?frm=ult
Citando:
"O que é indicado é que a marcação de exames deveria, a partir da adolescência, recair no período da tarde, com início às 15h, o que dará a adolescentes e jovens adultos "mais oportunidades de obter uma duração de sono adequada na véspera do exame".
Da mesma forma, e em relação aos horários escolares, Ana Allen Gomes considera que "deixam de estar ajustados" pelo menos a partir do 2.º ciclo do ensino básico: "Não se compreende por que motivo, à medida que a criança se torna mais velha e se aproxima da puberdade, os horários escolares se iniciem mais cedo, o que está em contradição com aquilo que é a tendência oposta com a entrada na puberdade, que é a de atraso [deslocação para mais tarde] do sistema circadiano, como é exemplo o ritmo sono-vigília, com tendência para o adolescente se deitar e levantar mais tarde", diz."

Origem de Parkinson poderá ser diferente

... O que pode levar a novos medicamentos que atrasem (ou até revertam) a doença:


http://www.independent.co.uk/life-style/health-and-families/health-news/parkinsons-disease-cure-breakthrough-leicester-university-a7098106.html
"(...) Leicester University researchers found most of the problem related to another part of the cell, called the endoplasmic reticulum (ER), they reported in the journal Cell Death and Disease.
In a study with fruit flies that had been genetically modified to develop Parkinson’s, the scientists managed to at least partially correct the problem so that the number of brain cells increased and the flies’ muscles remained healthy."

As pessoas incham...

... não se sabe muito bem porquê (não é bem assim, ver final). Podemos ver aqui algo que recentemente causou agitação nas redes sociais (RU): A mesma barriga com 12h de diferença:
http://www.dailymail.co.uk/femail/article-3651641/Tiffany-Brien-shares-photos-stomach-12-hours-apart-prove-bloats-like-else.html


PS. Alguns motivos para o inchaço abdominal:
http://senasecoisas.blogspot.pt/2016/06/sobre-o-inchaco-depois-de-comer.html?m=1

Cancro por infecção comum na vida marinha

http://www.independent.co.uk/news/science/cancer-contagious-infectious-sea-shellfish-a7095736.html

Sobre o uso indiscriminado de antibióticos na criação de animais

Parecido com o problema nos humanos:
http://www.pig-world.co.uk/news/animal-health/farm-antibiotics-investors-are-right-to-be-worried.html
"The need to tackle human prescribing is still widely considered to be the highest priority in the drive to safeguard our antibiotics, but global attention is increasingly turning to the overuse of antibiotics in farming.
The discovery in late 2015 of the mcr-1 gene, which confers resistance to the “last-resort” antibiotic colistin, catapulted veterinary antibiotic use into the headlines worldwide. First found in China, the gene was subsequently discovered in at least 19 countries worldwide.

These findings, strongly linked to farm use of colistin, triggered widespread concern. Subsequently, 50 medics and scientists across Europe and the US called on MEPs to support a ban on routine preventative mass-medication of groups of healthy animals."

Alternativa às estatinas aprovada no RU (colesterol)

http://www.express.co.uk/life-style/health/682284/cholesterol-drug-treatment-approved-NICE-NHS


Citando:



"Patients that have high levels of LDL cholesterol, an inherited form of high cholesterol levels and those who are statin intolerant will benefit.
Despite the widespread use of statins and other lipid-lowering therapies to reduce raised cholesterol levels, some people in the UK remain at significant risk of having a cardiovascular event and are unable to lower their cholesterol to levels indicated within national guidelines.
Alirocumab belongs to the most recent cholesterol-lowering class of treatments called PCSK9 inhibitors.
PCSK9 is a protein that plays an important role in managing ‘bad’ cholesterol by regulating the number of receptors for ‘bad’ cholesterol on the liver’s surface."

Teste de sangue para determinar risco de doenças cardiovasculares (a 5 anos)

http://www.independent.co.uk/news/science/blood-test-heart-attack-cardiovascular-disease-predicts-how-likely-in-next-five-years-a7091326.html


Citando:
"(...) patients with high levels of the immunoglobin G (IgG) antibody were less likely to suffer from cardiovascular disease, including stroke and heart attack, than those with lower levels, even when taking into account factors such as high blood pressure and cholesterol."

Exercício e melhorias na memorização

http://elitedaily.com/wellness/work-out-to-improve-your-memory/1530088/


Citando:
"Those who had delayed exercise [for 4 hours after studying] remembered their lesson 10 percent better than either of the other two groups. Moreover, the memory portion of their brains worked more efficiently during the tests."

Estudo sobre dores menstruais (e melhor forma de as combater)

http://www.independent.co.uk/life-style/health-and-families/health-news/period-pain-scientists-finally-work-out-why-menstruation-hurts-so-much-a7092981.html


Citando:
"Scientists have finally discovered why periods hurt so much, following a ground breaking study into menstrual pain.
Research has suggested PMS is caused by acute inflammation triggered by a biomarker called C-reactive protein (CRP). This indicates that the best way to battle the symptoms of PMS may be by using specific anti-inflammatory medications."

Quase metade da população adulta do RU (28 M) pode estar a sofrer de dor crónica

http://www.nhs.uk/news/2016/06June/Pages/Almost-half-of-all-UK-adults-may-be-living-with-chronic-pain.aspx


"The researchers used data from 19 studies that included almost 140,000 adults. They extrapolated the results to come up with the estimate that around 43% of people in the UK experience chronic pain [pain for more than 3 monthes]. More adults aged 75 or over (62%) experienced pain than those aged 18 to 25 (14.3%).
There are limitations to this study that affect the reliability, the main one being that this type of review can only be as good as the included studies. In this case, there weren't many good-quality studies and there was a lot of variation in their findings."

Medicamentos para diabetes relevantes para Alzheimer? (reutilização)

http://www.dailymail.co.uk/wires/pa/article-3652788/Scientists-diabetes-treatment-drugs-impact-Alzheimers-disease.html


Citando:
"Drugs used to treat diabetes may also be effective against Alzheimer's disease, new research suggests.
Scientists have found that the two conditions are strongly linked, raising the possibility of shared drug responses.
Medicines currently used to control glucose levels in diabetes may also alleviate the symptoms and progression of Alzheimer's, the team claims."

Sobre a resistência a antibióticos - The Economist

http://www.economist.com/news/leaders/21699116-how-combat-dangerous-rise-antibiotic-resistance-when-drugs-donu2019t-work


Citando:
"Resistance to antimicrobial medicines, such as antibiotics and antimalarials, is caused by the survival of the fittest. Unfortunately, fit microbes mean unfit human beings. Drug-resistance is not only one of the clearest examples of evolution in action, it is also the one with the biggest immediate human cost. And it is getting worse. Stretching today’s trends out to 2050, the 700,000 deaths could reach 10m. "

Second study this week links whole grains with long life | Reuters

Second study this week links whole grains with long life | Reuters

Cereais integrais associados a vida mais longa em 2 estudos recentemente publicados.
Citando:

"One serving of whole grains can be a half-cup of cooked brown rice, cooked oatmeal, or cooked 100 percent whole grain pasta, or one slice of 100 percent whole grain bread.

The BMJ review covered 45 studies involving more than 700,000 people altogether, and 100,000 deaths during follow-up. Researchers found the biggest difference in risk between people who ate two servings of whole grains per day and those who ate none. People who got two servings per day had lower risks of coronary heart disease, cardiovascular disease, death from stroke, cancer, respiratory disease, infectious disease and diabetes."

Relação entre bebidas quentes e cancro do esófago - OMS

http://www.jn.pt/nacional/interior/relacao-entre-bebibas-quentes-e-cancro-do-esofago-ja-era-suspeita-5229035.html

Link between cholesterol and heart disease in older people called into question | Daily Mail Online

Link between cholesterol and heart disease in older people called into question | Daily Mail Online

Concerns that saturated fats have been unfairly 'demonised' prompts Government advice re-think

Concerns that saturated fats have been unfairly 'demonised' prompts Government advice re-think

Citando:

"Current advice states that saturated fats should be restricted to 10 percent of the total calories consumed, following years of prevailing thought which linked it to an increased risk of heart disease.
Two studies in the last two years found no such link, however."

(...)

"It coincides with a controversial report last month by the National Obesity Forum which recommended that people eat more fat and fewer carbohydrates.

A report in the medical journal Open Heart last year said the government’s advice to reduce the amount of fat in the diet, introduced in 1983 in a bid to cut rates of coronary heart disease, was not supported by the scientific evidence available at the time, including the results of randomised controlled trials."

Técnica (in vitro) para reduzir o risco de passar aos filhos a "Mitocondrial Disease" testada com sucesso

http://m.ndtv.com/health/ivf-technique-that-cuts-genetic-disease-risk-found-safe-1418115


"(...) the new technique designed to reduce the risk of mothers passing on mitochondrial disease to their children, which is debilitating and often life-limiting.

Mitochondrial disease is a chronic, genetic disorder that occurs when the mitochondria of the cell fail to produce enough energy for cell or organ function, according to MitoAction, a US-based organisation working to improve quality of life for adults and children affected by the disease."

Microsoft usa dados de pesquisa para antecipar diagnóstico de Cancro Pancreático

https://www.washingtonpost.com/news/innovations/wp/2016/06/10/what-happens-when-your-search-engine-is-first-to-know-you-have-cancer/


Citando:
"The Microsoft researchers identified Web users who had recently searched for queries indicating they have pancreatic cancer, such as “I was told I have pancreatic cancer, what to expect,” and then looked back months earlier to examine patterns in the symptoms that the users searched for. This included phrases such as “dark or tarry stool,” “abdominal swelling,” “dark urine” and “yellowing skin.”
From this analysis they realized trends in the queries of users who were soon to be diagnosed with pancreatic cancer, identifying 5 to 15 percent of cases with low false-positive rates. The research was published in the Journal of Oncology Practice."

Poluição atmosférica ligada pela primeira vez a ataques debilitantes

http://m.timesofindia.com/life-style/health-fitness/health-news/Now-air-pollution-linked-to-strokes/articleshow/52699544.cms
Citando:
"Findings of the study show 90.5% of the stroke burden was attributable to "modifiable factors" such as smoking, eating too much sugar and not exercising enough, as well as the associated health problems, such as diabetes and heart disease.

 Doctors say changing lifestyle and habits in developing countries is a major concern for increasing burden of non-communicable diseases.

 The study also listed air pollution as a "modifiable factor", indicating efforts by the government and people can make a difference."
(...)
"Globally, about 15 million people suffer strokes every year, of which nearly 6 million die and 5 million are left disabled including loss of vision or speech, paralysis and confusion."

Contaminação por Listeria e recolha de snacks (Meningite)

Eis o que uma contaminação de sementes de girassol por Listeria pode provocar (a bactéria pode provocar septicemia ou meningite e é especialmente perigosa para idosos, crianças e grávidas): uma recolha em massa de lotes de produtos.
http://i.stuff.co.nz/business/80935731/meningitis-warning-as-food-watchdogs-recall-two-types-of-bounce-energy-balls


Citando:
"Listeria is rare but can lead to serious conditions among young people, the elderly and pregnant women, including meningitis."
(...)
"​Food Safety New Zealand says listeriosis is a rare but potentially life-threatening disease with a high death rate.
Listeria symptoms can be flu-like, including high temperature, aches, chills, vomiting and diarrhoea.
"Healthy adults are likely to experience only mild infection, causing flu-like symptoms or gastroenteritis.
"However, Listeria infection can occasionally lead to severe blood poisoning (septicaemia) or meningitis."

Leucemia do tipo AML tem afinal 11 subtipos

http://m.huffpost.com/uk/entry/uk_575926a4e4b014b4f2532f76?edition=uk&utm_hp_ref=uk
Citando:
"Researchers said that acute myeloid leukaemia (AML) is not a single disorder, but at least 11 different diseases comprising different constellations of genetic changes."
(...)
"They analysed more than 100 genes known to cause leukaemia, to identify common genetic themes behind the development of the disease.
They found that the patients were divided into at least 11 major groups, each with different constellations of genetic changes and distinctive clinical features."

Mutação de gene associada a certo tipo de Esclerose Múltipla

http://www.bbc.com/news/health-36416531
Citando:
"The mutation is in a gene called NR1H3, which makes a protein that acts as a switch controlling inflammation.
In MS the body's immune system mistakenly attacks the protective layer of myelin that surrounds nerve fibres in the brain and spinal cord, leading to muscle weakness and other symptoms."
(...)
"The researchers believe stopping the inflammation early might prevent or delay the disease. They already have drugs in mind that might do this by targeting the NR1H3 gene pathway.
These drugs are in development for other diseases, including cardiovascular disease and diabetes."
(...)
"[This MS] variant itself is rare and most people with MS won't have it. "

Parar a esclerose múltipla? - Estudo / Tratamento

http://www.bbc.com/news/health-36490315
Citando:
"The condition causes the immune system to attack the lining of nerves in the brain and spinal cord. Most patients are diagnosed in their 20s and 30s.
One existing treatment is for the immune system to be suppressed with chemotherapy and then stem cells are introduced to the patient's bloodstream - this procedure is known as an autologous haematopoietic stem cell transplant (HSCT).


(...)
But in this study, Canadian researchers went further - not just suppressing the immune system, but destroying it altogether.
It is then rebuilt with stem cells harvested from the patient's own blood which are at such an early stage, they have not developed the flaws that trigger MS.
The authors said that among the survivors, over a period of up to 13 years, there were no relapses and no new detectable disease activity."
(...) "1 person died".

RESOURCE: Comprehensive Cancer Information - NCI

Comprehensive Cancer Information (National Cancer Institute): http://www.cancer.gov/

Sub-sites:

• http://www.cancer.gov/about-cancer
• http://www.cancer.gov/types
• http://www.cancer.gov/types/prostate (ficha com informação por tipo de cancro)
• https://youtu.be/MXk0TufhiM8 (Video Series para os "mais visuais")

Bubbly drink trial 'to boost cancer therapy' - BBC News

Bubbly drink trial 'to boost cancer therapy' - BBC News



Citando:

"One reason thought to behind this is that cancers grow rapidly and their blood supply fails to keep up - leaving tumours with torturous, poorly-formed blood vessels that don't deliver oxygen-rich blood as well.

Prof Eleanor Stride, from Oxford University, says the lack of oxygen makes cancer cells "go into survival mode" making them more hardy and therefore less responsive to radiotherapy and drugs.

This is a particular problem for hard-to-treat cancers such as tumours of the pancreas, she says.

The team has already found that injecting oxygen in mice with cancer and then giving them chemotherapy leads to more successful treatments.

They recently carried out a small-scale trial of an oxygen-rich drink in mice.

The next stage is to repeat the mice experiments in much larger numbers, before human trials are considered.

But Prof Stride says: "I wouldn't suggest people rush out to buy any drinks claiming to be rich in oxygen."

Negative Emotions Are Key to Well-Being - Scientific American

Negative Emotions Are Key to Well-Being - Scientific American

Should You Get Tested for the Breast Cancer Genes? - Scientific American

Should You Get Tested for the Breast Cancer Genes? - Scientific American



Citando:

"The mostly common involved and most familiar breast cancer genes are the BRCA-1 and BRCA-2 genes. This sort of gene testing can be performed on blood, saliva, or even cheek swabbing.  The challenge? Hundreds of genes involving these two mutations have been discovered. Therefore, obtaining a complete test for all involved possibilities can cost up to 4,000 dollars. If patients meet certain criteria, however, insurance may cover up to 90% of the testing cost. What may be less costly and more simple, however, is if you already have an identified gene in another relative, in which testing can be more targeted and therefore much less costly."

Polémica com recomendação de aparelho para curar ou até prevenir cancro da próstata

http://www.telegraph.co.uk/news/2016/06/08/noel-edmonds-my-dad-died-of-ignorance-i-got-prostate-cancer-beca/


Citando:
""The medical profession can't even define the exact definition of health, but I'm encouraging people please don't do what my father did and die of ignorance," he said.
"We don't understand energy, that's why we have quantum physics and a bunch of people in CERN (the European Organization for Nuclear Research) trying to understand it.
"I could have gone down the same route. I believe pulsed electromagnetism has a role to play in tackling cancer and I will always believe that.""
(...)
"In a follow up statement, the company said: "Although research using very low frequency and intensity PEMF ([pulsed electromagnetic field) to help address cancer has produced some promising early results, it is currently in the very early stages and EMPpad does not make the claim that PEMF therapy can prevent cancer."


PS. Críticas ao autor dos comentários:
http://www.dailymail.co.uk/femail/article-3634373/JAN-MOIR-Noel-know-insults-victim-cancer.html

Anti-depressivos ineficazes em jovens - Estudo

Sabiam desta?
"(...)only a limited amount of research has been done on antidepressant use in children and teens."
Dados os efeitos secundários é surpreendente que sejam tão receitados a jovens.


http://www.cbsnews.com/news/most-antidepressants-ineffective-in-teens-study/
Citando:
"The findings show that out of 14 antidepressants, only fluoxetine (sold under brand names Prozac and Sarafem) was more effective at relieving symptoms of depression in young people than a placebo pill. In contrast, taking venlafaxine (Effexor) was associated with an increased risk of suicidal thoughts and suicide attempts when compared to a placebo and five other antidepressants."
"

Dúvidas nas recomendações para prolongar tratamento cancro da mama

http://www.m.webmd.com/a-to-z-guides/news/20160606/longer-use-of-certain-drugs-cuts-recurrence-for-breast-cancer-survivors (relacionado com este artigo anterior)

Citando:
"Many survivors of breast cancers that are sensitive to estrogen are advised to take hormone-suppressing drugs such as tamoxifen for five years, to cut their odds for a recurrence.
Tamoxifen can have onerous side effects, however. Now, new research finds that taking an alternative, and less troublesome, class of medications for a full decade can reduce the risk for recurrence even more -- without affecting a woman's quality of life.
The newer class of hormone-suppressing drugs are called aromatase inhibitors, and include drugs such as letrozole (Femara), anastrozole (Arimidex) and exemestane (Aromasin)."


Críticas / reservas:
http://www.forbes.com/sites/elaineschattner/2016/06/08/major-report-touts-benefits-of-prolonged-femara-use-after-breast-cancer-im-not-convinced/#55fdca8134ff


"

Um espectrómetro na palma das mãos?...

A Pocket Molecular Sensor For All to scan materials and/or physical objects and get instant relevant information to your smartphone (on food, medicine, and more):

https://www.consumerphysics.com/myscio/

Criticisms here:
http://www.cnet.com/news/kickstarter-science-beware-the-marketing-hype/

PS. Será que finalmente vamos poder saber se as uvas trazem sulfitos e em que quantidade? O vinho?  Herbicidas? etc.

Acerca de alguns "boatos" sobre o cancro...

... que por vezes circulam na Internet.

Não que ache propriamente falsas algumas das afirmações abaixo, é interessante ter a própria escola de medicina Johns Hopkins a opinar sobre os temas infra com propriedade:

The Hoax: Everyone Has Cancer Cells
The Hoax: A Strong Immune System Destroys Cancer
The Hoax: Cancer is Caused by Nutritional Deficiencies and Supplements Will Correct Them
The Hoax: Chemotherapy and Radiation Therapy Harms Normal Cells. Surgery Causes Cancer to Spread
The Hoax: Cancers Feed on Certain Foods
The Hoax: Cancer is a Disease of Mind, Body and Spirit
The Hoax: Oxygen Kills Cancer Cells

Do statins really age you faster? | Science | The Guardian

Do statins really age you faster? | Science | The Guardian

Sobre a canábis - Guardian

Mais um artigo de fundo do Guardian sobre drogas.
Desta vez o tema é a canábis:
https://www.theguardian.com/science/sifting-the-evidence/2016/may/19/say-why-to-drugs-the-highs-and-lows-of-cannabis

Sobre o Boletim Polínico (publicado pela SPAIC)

O Boletim Polínico é publicado regularmente pela Sociedade Portuguesa de Alergologia e Imunologia Clínica (SPAIC) em http://www.rpaerobiologia.com/boletim-polinico.

Referências ao Boletim Polínico aparecem frequentemente como notícias / avisos na comunicação social. p.e.:

• http://www2.portaldasaude.pt/portal/conteudos/a+saude+em+portugal/noticias/polenes29_05.htm
• Alergias: Pólenes muito elevados em Castelo Branco | Reconquista

Informação adicional

• Dicionário do Pólen: http://www.rpaerobiologia.com/dicionario-do-polen
• Recomendações ao doente (como minimizar alergias): http://www.rpaerobiologia.com/recomendacoes-ao-doente
• Calendário Polínico (medições do nível de pólen, últimos 3 meses apenas): http://www.rpaerobiologia.com/medicoes (exemplo mais complexo com query strings: http://www.rpaerobiologia.com/medicoes?date_start=2016-05-23&date_end=2016-05-29&regioes=6,8,3,9,5,4,2,7,1&polens= ou http://www.rpaerobiologia.com/medicoes?date_start=2016-05-23&date_end=2016-05-29&regioes=2,7,1&polens=betulaceae,chenopodiaceae,compositae,cupressaceae,oleaceae,plantaginaceae,platanaceae,poaceae,quercus,urticaceae,concentracao_polinica)
• Para subscrever a Newletter e receber periodicamente no seu e-mail informação com conteúdo personalizado use a acção no fundo da página em http://www.rpaerobiologia.com/dicionario-do-polen#:

Terapia de hormonas por 10 anos em vez de 5 (estudo Cancro Mama)

Um estudo vantajoso para... As farmacêuticas e não só?


http://www.theguardian.com/society/2016/jun/05/breast-cancer-drugs-decade-study-aromatase-inhibitors


Citando:
"Women should be offered 10 years of drugs to prevent the return of breast cancer, rather than five as now, according to a major study showed longer-term treatment reduced the numbers whose disease came back.
Huge numbers of women in the UK and around the world are already taking hormone therapy – drugs that block oestrogen in the body that can fuel breast cancer growth. Many abandon them within the first few years because of the side-effects or because they feel well and do not want to be on medication."

Recuperação de mobilidade com células estaminais depois de AVC (até 3 anos depois)

A fonte da notícia é chinesa mas já a vi noutros lados (e o pequeno estudo é de Stanford):
http://news.xinhuanet.com/english/2016-06/06/c_135414635.htm


Citando: "In an "unprecedented" clinical trial, U.S. researchers have successfully reversed the long-term debilitating effects in some of the stroke patients by injecting stem cells directly into their brains.
"This wasn't just, 'They couldn't move their thumb, and now they can,'" lead author Gary Steinberg, professor and chair of neurosurgery at the Stanford University School of Medicine, said in a statement.
"Patients who were in wheelchairs are walking now," said Steinberg, who led the 18-patient trial and conducted 12 of the procedures himself."
(...)
"The stem cells, called SB623, are derived from the bone marrow of adult donors and modified to beneficially alter the cells' ability to restore neurologic function."

Crocs (calçado) e a saúde dos pés

Aparentemente os especialistas dizem que não são a coisa mais saudável do mundo para os pés. E que não devem ser usadas mais do que 8-10h/dia:
http://www.express.co.uk/life-style/life/676953/crocs-ruining-feet-says-podiatrist-ugly-shoes-should-not-be-work-all-day
E o artigo diz que são feias. ;)

Exemplo de Press Release de Ensaios Clínicos

Um exemplo de PR com que me cruzei por estes dias com referência às diversas fases dos ensaios, os efeitos secundários detectados e os eventos de determinada gravidade (SAEs Grade 1-5).
Interessante (mas não surpreendente) o sítio aonde é publicado: Uk.finance.yahoo.com.


Ignyta Announces Interim Data from Phase 1 Clinical Trial of Investigational Precision Medicine RXDX-105 at ASCO 2016:
https://uk.finance.yahoo.com/news/ignyta-announces-interim-data-phase-130000822.html

Alimentos e sensação de bem-estar

In Público, 2016-06-05, p.19:
Bananas, ovos e frutos secos, (...) são ricos em triptofano, uma substância que proporciona uma sensação de bem-estar.

Padrões de sono (e alimentação) irregulares e riscos de ataque

http://www.dailymail.co.uk/health/article-3622707/Shift-work-REALLY-kill-Irregular-sleeping-eating-patterns-increase-worker-s-risk-severe-stroke.html


AVC.

Sobre os mosquitos, as picadas e como evitá-las

Excelente artigo que dá alguns possíveis motivos para que algumas pessoas sejam mais picadas do que outras (tipo de sangue, substâncias exaladas, bactérias na pele, temperatura corporal, cor da roupa...) e sobre os diversos tipos de repelentes de insectos (e a sua segurança e eficácia):
 http://www.irishnews.com/lifestyle/holidays/2016/06/01/news/how-to-avoid-and-treat-mosquito-bites-on-holiday-542874/


Citando:
"(...) [20%] DEET will protect the wearer for about five hours.
Other chemical agents available include icaridin and IR3535"
(...)
"Staphylococcus epidermidis [skin bacteria] make individuals more attractive to mosquitoes whilst others e.g. Pseudomonas aeruginosa [do the opposite]"

Sobre o inchaço depois de comer

Depois do artigo sobre peidos - mais suavemente dito, gases - faltava o artigo sobre o inchaço abdominal depois de comer...


De onde vem? Que alimentos o potenciam ou minimizam? Ver as 14 páginas seguintes:
http://www.health.com/health/m/gallery/0,,20802995,00.html

Vem aí o comprimido da saciedade (que ajuda na perda de peso)...

... Daqui a 3 anos:
http://www.dailymail.co.uk/news/article-3623002/The-bitter-pill-dieters-keen-swallow-Substance-plants-fool-body-believing-full.html


Citando:
"A natural substance found in plants could help those on a diet lose weight – although they may find it a bitter pill to swallow.
For food scientists have discovered that the tart-tasting chemical fools the body into feeling full.
Just which plant it comes from is a trade secret, but the Amarasate supplement, as it has been named, could be on sale in three years' time."
(...) "Extremely bitter and calorie-free, it tricks the gut into releasing especially large amounts of three appetite hormones called CCK, GLP-1 and PYY."

Sobre o tabaco - Guardian

Artigo de fundo sobre o tabaco e alguns mitos associados:
https://www.theguardian.com/science/sifting-the-evidence/2016/jun/02/say-why-to-drugs-the-smoke-and-mirrors-of-tobacco-cigarettes-harm
PS. Também em podcast.

A novela do Glifosato continua: mais um ano para decidir

Citando:
"Comissão Europeia quer congelar a decisão sobre o glifosato pelo menos um ano."
(...)
"O glifosato encontra-se em herbicidas de uso corrente, como o Round-Up da Monsanto, bem como dos concorrentes Syngenta, BASF, Bayer, Dupont e Dow Agrosciences. No entanto, a CE preparou uma segunda proposta para “minimizar” a utilização do glifosato nos jardins, parques e em zonas de jogos públicos, bem como nos campos agrícolas no período que precede as colheitas."


A autorização expira em Junho e em PT o uso já foi proibido.

Hormona PYY e remissão da Diabetes tipo 2

http://www.express.co.uk/life-style/health/663279/Diabetes-breakthrough-Scientists-discover-disease-remission?_ga=1.266621065.645149453.1449666565
Citando:
"Tests showed how a gut hormone restores normal blood glucose levels in Type 2 sufferers after gastric surgery.
The majority of obese patients are cured of the condition within hours of going under the knife and before any noticeable weight loss.
Breakthrough research by British and Norwegian scientists suggests a little-known hormone responsible for appetite suppression called PYY is behind the "magical effect"."
(...)
"Not all patients would be eligible for surgery so the ultimate aim is to replicate the beneficial effect surgery-free."

Dieta radical é melhor maneira de prevenir diabetes do tipo 2

http://www.express.co.uk/life-style/health/675231/Diet-halt-diabetes-revealed-How-weight-loss-slashes-risk-developing-disease

Citando:
"With evidence from other studies, we can be confident the 10.8 per cent weight loss from the diet, if maintained, would be associated with a 90 per cent reduction in diabetes risk over three years.”
(...) “The more weight lost and maintained, the greater the proportion of people who remain diabetes-free. They need to lose and keep off about 10 per cent of their weight.”

Melhor terapia para cancro na próstata - Estudo

http://www.yorkshireeveningpost.co.uk/news/health/prostate-cancer-treatment-developed-in-leeds-is-hailed-in-new-study-1-7937452
Citando:
"New has found that an ingenious prostate cancer treatment offers the best chance of long-term survival.
LDR brachytherapy provides patients with a form of internal radiotherapy as radioactive seeds are implanted into the prostate gland in a procedure lasting less than an hour."

Portugal tem 71 praias com zero de poluição

Portugal tem 71 praias com zero de poluição, Gaia e Vila do Bispo lideram:
http://observador.pt/2016/06/01/portugal-tem-71-praias-com-zero-de-poluicao-gaia-e-vila-do-bispo-lideram/
3 anos seguidos sem registo de escherichia coli ou enterococos intestinais (dados originais da Agência Portuguesa do Ambiente, estudo da Zero. 579 zonas balneares (algumas interiores).

Cancro da pele e imunoterapia

http://www.mirror.co.uk/science/skin-cancer-cure-hope-millions-8083885


"Experts has successfully treated a 53-year-old who was suffering from metastatic melanoma using two different types of immunotherapy."