https://stv.tv/news/east-central/1388531-scientists-find-key-gene-in-incurable-bowel-disorders/
Citando:
"The gene, known as MDR1, governs an important extractor system for toxins in the gut, removing damaging substances from intestinal cells, scientists said.
A research team, led by the University of Edinburgh, showed that MDR1 function was lower in people with inflamed IBD compared with those without inflammation.
Experts then showed that mice without MDR1 had faulty mitochondria, parts of the cell known as "batteries", which play a vital role in energy generation and cell health.
This mitochondrial dysfunction then resulted in colitis, inflammation of the inner lining of the bowel - a defining feature of IBD."
