Efeito protector do exercício físico mesmo quando há predisposição genética:
http://m.huffpost.com/us/entry/us_588fb5d5e4b02772c4e88c56
Citando:
"The study found that older adults who reported being sedentary most of the time were just as likely to develop dementia as people who are genetically predisposed to cognitive problems. (...)
And that’s significant, considering the gene that predisposes an individual to developing dementia makes you three to four times more likely to be diagnosed with a problem like Alzheimer’s disease, Parkinson’s disease or Lewy body disease.
“The important message here is that being inactive may completely negate the protective effects of a healthy set of genes,” co-author of the study Jennifer Heisz, assistant professor in the Department of Kinesiology at McMaster University, told The Huffington Post.
And remember, the majority of individuals do not carry the genetic risk for dementia in the first place, she added.
The upside to the research is that it suggests even a little bit of regular exercise could go a long way in terms of helping prevent cognitive problems for a lot of people, Heisz said.
Walking just three times a week was linked to big benefits
For the study, 1,646 adults 65 or older had their blood analyzed for the presence of the apolipoprotein E allele, the gene known to be most strongly associated with dementia. No one in the study had dementia or any cognitive impairment at the start of the study.
Follow-up data collected five years after the study began showed that 331 individuals had subsequently been diagnosed with some form of dementia. The researchers also collected survey responses about whether those in the study exercised regularly.
Unsurprisingly, the data showed the odds of developing dementia over the course of the study were two times greater in individuals with the dementia allele than for those without the allele. And the data also showed that the individuals who reported not exercising regularly similarly had nearly twice the odds of developing dementia compared with the individuals without the dementia allele.
“You don’t have to train like an Olympian to get the brain health benefits of being physically active.
The people in the study who indicated they exercised regularly were asked two follow-up questions about their exercise habits. A majority of the study participants said walking was their primary exercise and that they did it approximately three times per week.
It’s important to point out a fairly minimal amount of exercise was found to have a big effect when it comes to dementia risk, Heisz noted. “You don’t have to train like an Olympian to get the brain health benefits of being physically active,” she said.
Experts still have questions about what type of exercise is best
This study is still epidemiological data, Heisz noted ― which means it shows a link between sedentary behavior and dementia risk, but doesn’t necessarily explain how one leads to the other.
But taken with previous research that has linked physical activity is to lower dementia risk, the results are fairly convincing, she added. This study included a large number of individuals, it followed those individuals for five years and it controlled for other dementia risk factors, including age, heart disease, stroke, diabetes, high blood pressure, depression and smoking.
More studies are needed to identify what types of exercise provide the most benefit in terms of preventing dementia, she said ― as well as to determine the exact mechanisms in the brain that make physical activity protective when it comes to cognitive decline.
“If a physician were to ask us today what type of exercise to prescribe for a patient to reduce the risk of dementia, the honest answer is ‘we really don’t know,’” another study co-author, Barbara Fenesi, a postdoctoral fellow at McMaster, noted in a press release.
The group is conducting another study comparing different types of exercise ― including high-intensity training and moderate continuous training ― to start to answer some of those questions.
The important message here is that some physical activity does appear to be beneficial ― and being sedentary appears to increase dementia risk, Heisz said.
Watch the video below to hear more about what neurologists have to say about how even a small amount of exercise can do a lot in terms of preventing memory loss.
This reporting is brought to you by HuffPost’s health and science platform, The Scope. Like us on Facebook and Twitter and tell us your story: scopestories@huffingtonpost.com.
Sarah DiGiulio is The Huffington Post’s sleep reporter. You can contact her at sarah.digiulio@huffingtonpost.com.
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"The upside to the research is that it suggests even a little bit of regular exercise could go a long way in terms of helping prevent cognitive problems for a lot of people, Heisz said.
Walking just three times a week was linked to big benefits
For the study, 1,646 adults 65 or older had their blood analyzed for the presence of the apolipoprotein E allele, the gene known to be most strongly associated with dementia. No one in the study had dementia or any cognitive impairment at the start of the study."
(...)
"More studies are needed to identify what types of exercise provide the most benefit in terms of preventing dementia, she said ― as well as to determine the exact mechanisms in the brain that make physical activity protective when it comes to cognitive decline. "
Mostrar mensagens com a etiqueta 2017-01. Mostrar todas as mensagens
Mostrar mensagens com a etiqueta 2017-01. Mostrar todas as mensagens
quarta-feira, 1 de fevereiro de 2017
terça-feira, 31 de janeiro de 2017
O teste ao cancro por análise ao hálito (revisitado pelo NHS)
A análise do NHS (que é o SNS do Reino Unido) às notícias que circularam recentemente (o estudo é muito preliminar, não estava disponível para análise e ainda é muito cedo para se saber se poderá ser utilizado para construir o tal "breathaliser"):
http://www.nhs.uk/news/2017/01January/Pages/breath-test-shows-potential-for-detecting-cancer.aspx
Citando:
"The study is currently only available as a published protocol and poster presentation with accompanying press release. A full study publication is not available so we can't fully critique the methods and analysis.
Worldwide, OGC cancers account for around 1.4 million diagnoses a year but diagnosis tends to be late and therefore survival rates are low.
At the moment these cancers can only be diagnosed using endoscopy, which involves a camera attached to a flexible tube being passed down the throat. The procedure can be uncomfortable and is costly to the NHS.
A breath test that is able to identify the "chemical signature" of a cancer could be an ideal way to indicate a cancer diagnosis and help decide whether further invasive investigations are needed. It would hopefully enable more patients to be diagnosed at an earlier stage of the disease."
http://www.nhs.uk/news/2017/01January/Pages/breath-test-shows-potential-for-detecting-cancer.aspx
Citando:
"The study is currently only available as a published protocol and poster presentation with accompanying press release. A full study publication is not available so we can't fully critique the methods and analysis.
Worldwide, OGC cancers account for around 1.4 million diagnoses a year but diagnosis tends to be late and therefore survival rates are low.
At the moment these cancers can only be diagnosed using endoscopy, which involves a camera attached to a flexible tube being passed down the throat. The procedure can be uncomfortable and is costly to the NHS.
A breath test that is able to identify the "chemical signature" of a cancer could be an ideal way to indicate a cancer diagnosis and help decide whether further invasive investigations are needed. It would hopefully enable more patients to be diagnosed at an earlier stage of the disease."
segunda-feira, 30 de janeiro de 2017
Sobre o Sodium Benzoate (E211, Benzoato de Sódio)
Sobre o E211 que me apareceu como conservante nuns insuspeitos pickles de manga picantes indianos (bem salgados por sinal):
https://en.m.wikipedia.org/wiki/Sodium_benzoate
Referências finais interessantes: (como funciona como conservante - alterando a alcalinidade) e interacções com outros ingredientes (Vitamina C ou E300 e outros), formação de benzeno (potencialmente cancerígeno) e a remoção generalizada de bebidas.
Citando:
"[Mecanismo de preservação] The mechanism starts with the absorption of benzoic acid into the cell. If the intracellular pH falls to 5 or lower, the anaerobic fermentation of glucose through phosphofructokinase decreases sharply, which inhibits the growth and survival of microorganisms that cause food spoilage."
(...)
"A paper published in the March 2015 Journal of the Science of Food and Agriculture found that sodium benzoate has been replaced by potassium sorbate in the majority of soft drinks in the United Kingdom to avoid the use of anything the consumer might consider an additive, particularly in connection with colours and preservatives.
Association with benzene in soft drinks:
In combination with ascorbic acid (vitamin C, E300), sodium benzoate and potassium benzoate may form benzene, a known carcinogen. When tested by the FDA, most beverages that contained both ascorbic acid and benzoate had benzene levels that were below those considered dangerous for consumption by the World Health Organization (5 ppb).
Most of the beverages that tested higher have been reformulated and subsequently tested below the safety limit.
Heat, light and shelf life can increase the rate at which benzene is formed."
Fonte: Wikipedia (e cada uma das frases tem citação disponível no artigo original, editado por brevidade).
Actualizado: 2017-01-31 com detalhes do mec.pres. e benzeno.
https://en.m.wikipedia.org/wiki/Sodium_benzoate
Referências finais interessantes: (como funciona como conservante - alterando a alcalinidade) e interacções com outros ingredientes (Vitamina C ou E300 e outros), formação de benzeno (potencialmente cancerígeno) e a remoção generalizada de bebidas.
Citando:
"[Mecanismo de preservação] The mechanism starts with the absorption of benzoic acid into the cell. If the intracellular pH falls to 5 or lower, the anaerobic fermentation of glucose through phosphofructokinase decreases sharply, which inhibits the growth and survival of microorganisms that cause food spoilage."
(...)
"A paper published in the March 2015 Journal of the Science of Food and Agriculture found that sodium benzoate has been replaced by potassium sorbate in the majority of soft drinks in the United Kingdom to avoid the use of anything the consumer might consider an additive, particularly in connection with colours and preservatives.
Association with benzene in soft drinks:
In combination with ascorbic acid (vitamin C, E300), sodium benzoate and potassium benzoate may form benzene, a known carcinogen. When tested by the FDA, most beverages that contained both ascorbic acid and benzoate had benzene levels that were below those considered dangerous for consumption by the World Health Organization (5 ppb).
Most of the beverages that tested higher have been reformulated and subsequently tested below the safety limit.
Heat, light and shelf life can increase the rate at which benzene is formed."
Fonte: Wikipedia (e cada uma das frases tem citação disponível no artigo original, editado por brevidade).
Actualizado: 2017-01-31 com detalhes do mec.pres. e benzeno.
sábado, 28 de janeiro de 2017
Carência de vitamina B3 e demência?
Nos homens é uma suspeita, nos ratos foi confirmado (e devido a uma alimentação baseada apenas em milho por falta de mais diversidade em França):
https://www.theguardian.com/world/2017/jan/28/frances-wild-hamsters-being-turned-into-crazed-cannibals-by-diet-of-corn#img-1
Citando:
"The monotonous diet is leaving the animals starving, scientists discovered almost by accident. The problem is a lack of vitamins. In fact, one in particular: B3, or niacin.
Researchers led by Mathilde Tissier at the University of Strasbourg had set out to determine whether hamster diet affects their ability to reproduce in the wild.
Earlier work had looked at the impact of pesticides and mechanised ploughing, which can destroy their underground homes, especially during hibernation in winter. But the possible link with what they eat remained unexplored."
(...)
"In a second set of experiments, they offered hamsters corn-based diets, one of them with B3 added. Sure enough, the vitamin-enriched diet was enough to eliminate the horrific symptoms, and prevent the female hamsters from eating their young.
The dire consequences of the B3-deficient corn diet, the scientists concluded, stemmed not from reduced maternal hormones, but rather a change in the nervous system that induced the same “dementia-like” behaviour diagnosed in humans."
https://www.theguardian.com/world/2017/jan/28/frances-wild-hamsters-being-turned-into-crazed-cannibals-by-diet-of-corn#img-1
Citando:
"The monotonous diet is leaving the animals starving, scientists discovered almost by accident. The problem is a lack of vitamins. In fact, one in particular: B3, or niacin.
Researchers led by Mathilde Tissier at the University of Strasbourg had set out to determine whether hamster diet affects their ability to reproduce in the wild.
Earlier work had looked at the impact of pesticides and mechanised ploughing, which can destroy their underground homes, especially during hibernation in winter. But the possible link with what they eat remained unexplored."
(...)
"In a second set of experiments, they offered hamsters corn-based diets, one of them with B3 added. Sure enough, the vitamin-enriched diet was enough to eliminate the horrific symptoms, and prevent the female hamsters from eating their young.
The dire consequences of the B3-deficient corn diet, the scientists concluded, stemmed not from reduced maternal hormones, but rather a change in the nervous system that induced the same “dementia-like” behaviour diagnosed in humans."
sexta-feira, 27 de janeiro de 2017
Detecção de Sulfitos nos alimentos?
Os sulfitos (SO2) estão em muitos lados: No vinho, na fruta (uvas), em certos pós de caril, etc.
É possível detectar em que quantidades e no momento (ou quase)?
Talvez (artigo científico):
https://www.researchgate.net/publication/222433101_Simple_methods_for_rapid_determination_of_sulfite_in_food_products
Citando:
PRA-formaldehyde method
DTNB method
FFR: Pesquisa de aplicações no mercado
É possível detectar em que quantidades e no momento (ou quase)?
Talvez (artigo científico):
https://www.researchgate.net/publication/222433101_Simple_methods_for_rapid_determination_of_sulfite_in_food_products
Citando:
PRA-formaldehyde method
DTNB method
FFR: Pesquisa de aplicações no mercado
Ai a acrilamida (potencialmente cancerígena) e o McDonald's
http://www.counselheal.com/articles/31468/20170126/mcdonalds-taking-steps-reduce-cancer-causing-chemicals-food.htm
Citando:
"McDonald's reported to have been taking measures in the reduction of acrylamide in its food. For the past decade they have changed the variety and type of potatoes they use that have less starch. They have introduced new storage methods and processing conditions to limit the risk of acrylamide formation.
Acrylamide is formed when sugars and proteins in starchy foods are roasted, fried, baked or toasted. It causes a chemical reaction at high temperatures around 120 degrees Celsius and above."
(...)
"FSA experts have also advised not to store potatoes in the fridge, this is a process called cold sweetening because cold temperatures can increase formation of acrylamide. The longer the potatoes are kept in the fridge the greater the risks.
Some critics argued that the acrylamide health effects on humans are extremely weak. Animal studies have linked acrylamide health risks but there are no current studies that have strong evidence any link of these risks to humans."
Citando:
"McDonald's reported to have been taking measures in the reduction of acrylamide in its food. For the past decade they have changed the variety and type of potatoes they use that have less starch. They have introduced new storage methods and processing conditions to limit the risk of acrylamide formation.
Acrylamide is formed when sugars and proteins in starchy foods are roasted, fried, baked or toasted. It causes a chemical reaction at high temperatures around 120 degrees Celsius and above."
(...)
"FSA experts have also advised not to store potatoes in the fridge, this is a process called cold sweetening because cold temperatures can increase formation of acrylamide. The longer the potatoes are kept in the fridge the greater the risks.
Some critics argued that the acrylamide health effects on humans are extremely weak. Animal studies have linked acrylamide health risks but there are no current studies that have strong evidence any link of these risks to humans."
Carência de vitamina A na mãe pode afectar Alzheimer no filho 65 anos depois?
Parece que sim (em ratos):
http://www.mirror.co.uk/lifestyle/health/alzheimers-begin-womb-because-mums-9700947
Alimentos ricos em vitamina A (citação):
"Foods rich in the vitamin include sweet potatoes, tomatoes, spinach, cabbage, carrots, lettuce, grapefuit, mango, watermelon and apricots.
Other good sources are cod liver oil, liver and kidney. Smaller amounts are found in butter, full fat dairy products and margarine, oily fish and eggs."
Citando:
"In experiments on mice, his team found even a mild deficiency of vitamin A boosted production of amyloid beta in the brain.
This is one of the rogue proteins believed to be responsible for dementia by forming plaques that smother and destroy neurons, leading to loss of memory and confusion.
Mice that did not get enough vitamin A in the womb and infancy in the womb and infancy performed worse as adults on a standard test of learning and memory.
The researchers said these early developmental stages are crucial periods during which brain tissue is “programmed” for the rest of a person’s life."
http://www.mirror.co.uk/lifestyle/health/alzheimers-begin-womb-because-mums-9700947
Alimentos ricos em vitamina A (citação):
"Foods rich in the vitamin include sweet potatoes, tomatoes, spinach, cabbage, carrots, lettuce, grapefuit, mango, watermelon and apricots.
Other good sources are cod liver oil, liver and kidney. Smaller amounts are found in butter, full fat dairy products and margarine, oily fish and eggs."
Citando:
"In experiments on mice, his team found even a mild deficiency of vitamin A boosted production of amyloid beta in the brain.
This is one of the rogue proteins believed to be responsible for dementia by forming plaques that smother and destroy neurons, leading to loss of memory and confusion.
Mice that did not get enough vitamin A in the womb and infancy in the womb and infancy performed worse as adults on a standard test of learning and memory.
The researchers said these early developmental stages are crucial periods during which brain tissue is “programmed” for the rest of a person’s life."
quinta-feira, 26 de janeiro de 2017
Ansiedade e depressão relacionados com morte por cancro
https://stv.tv/news/scotland/1379060-anxiety-could-heighten-risk-of-dying-from-cancer-study-finds/
Citando:
"Dr David Batty from University College London, the lead author, said: "After statistical control for these factors, the results show that compared with people in the least distressed group, death rates in the most distressed group were consistently higher for cancer of the bowel, prostate, pancreas, and oesophagus and for leukaemia."
The researchers said the study did not prove distress definitely caused increased death, and it may be that undiagnosed cancer lowers people's mood."
Citando:
"Dr David Batty from University College London, the lead author, said: "After statistical control for these factors, the results show that compared with people in the least distressed group, death rates in the most distressed group were consistently higher for cancer of the bowel, prostate, pancreas, and oesophagus and for leukaemia."
The researchers said the study did not prove distress definitely caused increased death, and it may be that undiagnosed cancer lowers people's mood."
Nova combinação de drogas prolonga um pouco a esperança de vida (Cancro Pâncreas)
http://www.nhs.uk/news/2017/01January/Pages/New-drug-treatment-for-pancreatic-cancer-extends-survival.aspx
Citando:
"The trial showed people lived an average of 2.5 months longer if they took two drugs than if they took just one. Pancreatic cancer has a poor outlook compared with many other cancers.
Using information from the study, researchers estimated that the chances of people living for five years were 28.8% for those who took both drugs, compared with 16.3% for those treated with one drug.
However, not everyone involved in the trial was followed up for five years, so we don't know how reliable these longer-term estimates are.
The researchers say the two-drug combination should be "the new standard of care" for people who've had surgery for pancreatic cancer.
But people who took both drugs were more likely to stop treatment early because of the toxic side effects of chemotherapy.
This is an important consideration for people whose treatment can only prolong life and not achieve a cure, as there is always going to be a trade-off between survival time and quality of life."
Citando:
"The trial showed people lived an average of 2.5 months longer if they took two drugs than if they took just one. Pancreatic cancer has a poor outlook compared with many other cancers.
Using information from the study, researchers estimated that the chances of people living for five years were 28.8% for those who took both drugs, compared with 16.3% for those treated with one drug.
However, not everyone involved in the trial was followed up for five years, so we don't know how reliable these longer-term estimates are.
The researchers say the two-drug combination should be "the new standard of care" for people who've had surgery for pancreatic cancer.
But people who took both drugs were more likely to stop treatment early because of the toxic side effects of chemotherapy.
This is an important consideration for people whose treatment can only prolong life and not achieve a cure, as there is always going to be a trade-off between survival time and quality of life."
Ai a acrilamida (cancerígena) outra vez!
É um assunto recorrente, que vai voltando. Há uma campanha (Go for Gold - FSA) para ajudar as pessoas a minimizarem a exposição ajustando a forma de preparação dos alimentos. E há especialistas que relembram que os estudos mais aprofundados foram feitos em ratos (e que as quantidades a que somos expostos numa torrada queimada ou batatas assadas no forno são pequenas):
https://www.theguardian.com/science/2017/jan/23/ancer-risk-roast-potatoes-toast-acrylamide
http://www.telegraph.co.uk/opinion/2017/01/23/hands-roast-potatoes/
Citando (elsewhere):
"Today, the Food Standards Agency (FSA) launched a campaign called ‘Go for Gold’, urging people to understand how to minimise exposure to acrylamide when cooking at home.
It outlines that Acrylamide is a chemical created when foods, such as potatoes and bread, cooked for long periods at high temperatures when baking, frying, grilling, toasting and roasting, and has the potential to cause cancer in humans.
The campaign urges people to minimise levels of the potentially harmful chemical in home cooking. "
(...)
"Exposures 170mg per each kg of body weight are believed to be the point of an increased risk of cancer.
But dietary surveys revealed exactly how much acrylamide adults are exposed to on a daily basis.
For most people, the consumption of the toxic compound if less than 0.6mg, but many have as much as 1.1mg.
He said: “Adults with the highest consumption of acrylamide could consume 160 times as much and still only be at a level that toxicologists think unlikely to cause increased tumours"
https://www.theguardian.com/science/2017/jan/23/ancer-risk-roast-potatoes-toast-acrylamide
http://www.telegraph.co.uk/opinion/2017/01/23/hands-roast-potatoes/
Citando (elsewhere):
"Today, the Food Standards Agency (FSA) launched a campaign called ‘Go for Gold’, urging people to understand how to minimise exposure to acrylamide when cooking at home.
It outlines that Acrylamide is a chemical created when foods, such as potatoes and bread, cooked for long periods at high temperatures when baking, frying, grilling, toasting and roasting, and has the potential to cause cancer in humans.
The campaign urges people to minimise levels of the potentially harmful chemical in home cooking. "
(...)
"Exposures 170mg per each kg of body weight are believed to be the point of an increased risk of cancer.
But dietary surveys revealed exactly how much acrylamide adults are exposed to on a daily basis.
For most people, the consumption of the toxic compound if less than 0.6mg, but many have as much as 1.1mg.
He said: “Adults with the highest consumption of acrylamide could consume 160 times as much and still only be at a level that toxicologists think unlikely to cause increased tumours"
Algumas causas para o sexo doloroso (mulheres)
E agora para algo completamente diferente: sexo doloroso? Mulheres depois dos 50 e adolescentes são as que mais se queixam. Algumas destas condições são perfeitamente tratáveis:
http://www.express.co.uk/life-style/life/758880/painful-sex-causes
Citando:
“Some commercially vaginal lubricants can cause allergic reactions, so be aware of what you are putting on the delicate skin of your genitals. Latex products, such as condoms or sex toys, can produce an allergic reaction too – as well as some spermicidal creams.
“Vaginal thrush, bacterial vaginosis or sexually transmitted diseases such as chlamydia, gonorrhoea and genital herpes can all cause genital pain, so seek medical advice if you think you may have one of these conditions.
“They can all be easily treated with medication. Your partner may have to be treated too to prevent them passing it back to you.”"
http://www.express.co.uk/life-style/life/758880/painful-sex-causes
Citando:
“Some commercially vaginal lubricants can cause allergic reactions, so be aware of what you are putting on the delicate skin of your genitals. Latex products, such as condoms or sex toys, can produce an allergic reaction too – as well as some spermicidal creams.
“Vaginal thrush, bacterial vaginosis or sexually transmitted diseases such as chlamydia, gonorrhoea and genital herpes can all cause genital pain, so seek medical advice if you think you may have one of these conditions.
“They can all be easily treated with medication. Your partner may have to be treated too to prevent them passing it back to you.”"
terça-feira, 24 de janeiro de 2017
Suplemento Alimentar: Sobre o carvão activo (ou carvão activado)
Sobre o carvão activo (ou carvão activado, carvão vegetal, activated charcoal): Suplemento alimentar que contribui para a manutenção do processo digestivo e intestinal. Algumas embalagens alegam ajudar no combate à flatulência.
Os diversos suplementos alimentares que se vêem no mercado (PT) combinam o carvão activo sempre com mais algo (funcho, etc.).
Sobre a saúde digestiva e intestinal (com referência ao carvão vegetal):
https://www.celeiro.pt/conteudo/detalhe/as-plantas-medicinais-e-os-problemas-digestivos
Exemplos do suplemento alimentar (com preços, Celeiro.pt):
https://www.celeiro.pt/procurar#!/pesquisa:carvão/
O lítio associado a taxas reduzidas de suicídio e menor risco de Alzheimer?
Sim, está a ser estudada (na Escócia, Universidade de Glasgow) o efeito das exposição a pequenas quantidades de Lítio presente naturalmente em algumas águas.
O lítio já fez parte da bebida 7-Up até preocupações com a sua toxicidade e alterações na legislação da indústria de bebidas determinaram a sua retirada de produtos tendo permanecido em uso para efeitos psiquiátricos - tratamento da doença bipolar (as doses terapêuticas começam nos 300mg/dia - enquanto que o que nos pode chegar via a água canalizada não costuma passar os 2mg/dia).
O lítio não é patenteável, o que pode justificar a falta de entusiasmo (e investigação) sobre os seus efeitos.
Detalhes sobre oligo-elementos:
https://www.celeiro.pt/conteudo/detalhe/oligo-elementos
Fonte: "Os segredos dos remédios naturais - O guia definitivo para se manter saudável e feliz, dos superalimentos às terapias alternativas - BBC / G o o d y S A", num Continente perto de si.
O lítio já fez parte da bebida 7-Up até preocupações com a sua toxicidade e alterações na legislação da indústria de bebidas determinaram a sua retirada de produtos tendo permanecido em uso para efeitos psiquiátricos - tratamento da doença bipolar (as doses terapêuticas começam nos 300mg/dia - enquanto que o que nos pode chegar via a água canalizada não costuma passar os 2mg/dia).
O lítio não é patenteável, o que pode justificar a falta de entusiasmo (e investigação) sobre os seus efeitos.
Detalhes sobre oligo-elementos:
https://www.celeiro.pt/conteudo/detalhe/oligo-elementos
Fonte: "Os segredos dos remédios naturais - O guia definitivo para se manter saudável e feliz, dos superalimentos às terapias alternativas - BBC / G o o d y S A", num Continente perto de si.
domingo, 22 de janeiro de 2017
Mais sobre a higiene do sono
Sobre a higiene do sono, os motivos que podem estar a sabotar o nosso sono e recomendações para cada um deles:
http://www.gazettelive.co.uk/news/health/you-getting-enough-sleep-heres-12479496
Citando:
"As well as the new study by Aviva healthcare, an increasing raft of health research suggests it’s time we took our sleep even more seriously, as deprivation can have detrimental effects on everything from our brain power to blood pressure, and has even been linked to early death."
O estudo Health Checkup Report (Aviva, Reino Unido, 2015):
https://www.aviva.co.uk/healthcarezone/document-library/files/he/healthcheckukreport2015.pdf
http://www.gazettelive.co.uk/news/health/you-getting-enough-sleep-heres-12479496
Citando:
"As well as the new study by Aviva healthcare, an increasing raft of health research suggests it’s time we took our sleep even more seriously, as deprivation can have detrimental effects on everything from our brain power to blood pressure, and has even been linked to early death."
O estudo Health Checkup Report (Aviva, Reino Unido, 2015):
https://www.aviva.co.uk/healthcarezone/document-library/files/he/healthcheckukreport2015.pdf
sábado, 21 de janeiro de 2017
Mais sobre o exercício retardar o envelhecimento (e os telómeros)
http://www.ibtimes.com/how-look-younger-active-lifestyle-exercise-slows-aging-process-older-women-health-2478928
Citando:
"This study, which was published in the American Association for the Advancement of Science's journal, was able to identify the specific molecule, called NRF1, responsible for maintaining telomeres. Exercise, spending 45 minutes on a stationary bicycle in this case, reportedly boosted the levels of NRF1 and kept the cells "younger."
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"Think about NRF1 like varnish on nails,” Decottignies told TIME Magazine. “You cannot change the nail, but you can change the varnish again and again. What you’re doing is refreshing and replacing the old section with new protective molecules at the telomeres.”"
Citando:
"This study, which was published in the American Association for the Advancement of Science's journal, was able to identify the specific molecule, called NRF1, responsible for maintaining telomeres. Exercise, spending 45 minutes on a stationary bicycle in this case, reportedly boosted the levels of NRF1 and kept the cells "younger."
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"Think about NRF1 like varnish on nails,” Decottignies told TIME Magazine. “You cannot change the nail, but you can change the varnish again and again. What you’re doing is refreshing and replacing the old section with new protective molecules at the telomeres.”"
sexta-feira, 20 de janeiro de 2017
Estar o dia todo sentado acelera o envelhecimento (afecta ADN)
Artigo com métricas quantitativas interessantes relativas aos telómeros (e crítico negativamente acerca da utilidade do estudo sobre estar sentado acelerar o envelhecimento do ADN):
http://www.nhs.uk/news/2017/01January/Pages/Sitting-down-all-day-may-accelerate-DNA-ageing.aspx
Citando:
"Telomeres are measured in the small sections of nucleic acids that make up DNA, known as base pairs.
Among women in the study who did less than about 40 minutes of physical activity a day, those who sat longest had shorter telomeres by an average 170 base pairs.
The researchers say telomeres shorten at a rate of 21 base pairs a year – using a rough "back of a fag packet" calculation, 170 equals about eight years.
Sitting time did not seem linked to telomere length for women who did at least 30 minutes of physical activity a day."
http://www.nhs.uk/news/2017/01January/Pages/Sitting-down-all-day-may-accelerate-DNA-ageing.aspx
Citando:
"Telomeres are measured in the small sections of nucleic acids that make up DNA, known as base pairs.
Among women in the study who did less than about 40 minutes of physical activity a day, those who sat longest had shorter telomeres by an average 170 base pairs.
The researchers say telomeres shorten at a rate of 21 base pairs a year – using a rough "back of a fag packet" calculation, 170 equals about eight years.
Sitting time did not seem linked to telomere length for women who did at least 30 minutes of physical activity a day."
Motivo pelo qual doentes com Alzheimer se perdem?
O motivo é agora melhor conhecido:
http://www.mirror.co.uk/science/scientists-discovered-dementia-patients-lost-9654193
Citando:
"The findings raise the possibility that spatial disorientation could be treated by correcting this imbalance through transcranial stimulation, deep-brain stimulation, or light-based therapy.
Dr Duff concluded: “In the meantime our findings suggest that it may be possible to develop navigation-based cognitive tests for diagnosing Alzheimer’s disease in its initial stages"
http://www.mirror.co.uk/science/scientists-discovered-dementia-patients-lost-9654193
Citando:
"The findings raise the possibility that spatial disorientation could be treated by correcting this imbalance through transcranial stimulation, deep-brain stimulation, or light-based therapy.
Dr Duff concluded: “In the meantime our findings suggest that it may be possible to develop navigation-based cognitive tests for diagnosing Alzheimer’s disease in its initial stages"
Tratamento novo para cancro da próstata (bactérias tóxicas activadas por luz)
Algo ainda em ensaios com um enorme potencial (dado que todas as opções actuais envolvem riscos elevadíssimos de efeitos secundários terríveis para os homens - impotência e incontinência):
http://www.bbc.com/news/health-38304076
Citando:
"The new treatment uses a drug, made from bacteria that live in the almost total darkness of the seafloor and which become toxic only when exposed to light.
Ten fibre optic lasers are inserted through the perineum - the gap between the anus and the testes - and into the cancerous prostate gland.
When the red laser is switched on, it activates the drug to kill the cancer and leaves the healthy prostate behind."
http://www.bbc.com/news/health-38304076
Citando:
"The new treatment uses a drug, made from bacteria that live in the almost total darkness of the seafloor and which become toxic only when exposed to light.
Ten fibre optic lasers are inserted through the perineum - the gap between the anus and the testes - and into the cancerous prostate gland.
When the red laser is switched on, it activates the drug to kill the cancer and leaves the healthy prostate behind."
Alternativa de biópsia à próstata com maior taxa de detecção
Evolução interessante uma vez que a biópsia tinha efeitos secundarios possíveis como disfunção eréctil e uma taxa de detecção correcta (de tumores agressivos que requerem atenção imediata) muito baixa:
http://www.bbc.com/news/health-38665618
Citando:
"The biggest leap in diagnosing prostate cancer "in decades" has been made using new scanning equipment, say doctors and campaigners.
Using advanced MRI nearly doubles the number of aggressive tumours that are caught.
And the trial on 576 men, published in the Lancet, showed more than a quarter could be spared invasive biopsies, which can lead to severe side-effects.
The NHS is already reviewing whether the scans can be introduced widely.
Prostate cancer is the most common cancer in British men (...)"
"If men have high prostate specific antigen (PSA) levels in the blood, they go for a biopsy.
Twelve needles then take random samples from the whole of the prostate.
It can miss a cancer that is there, fail to spot whether it is aggressive, and cause side-effects including bleeding, serious infections and erectile dysfunction.
"Taking a random biopsy from the breast would not be accepted, but we accept that in prostate," said Dr Hashim Ahmed, a consultant and one of the researchers.
Around 100,000 to 120,000 men go through this every year in the UK."
(...)
"93% of aggressive cancers were detected by using the MRI scan to guide the biopsy compared with just 48% when the biopsy was done at random."
http://www.bbc.com/news/health-38665618
Citando:
"The biggest leap in diagnosing prostate cancer "in decades" has been made using new scanning equipment, say doctors and campaigners.
Using advanced MRI nearly doubles the number of aggressive tumours that are caught.
And the trial on 576 men, published in the Lancet, showed more than a quarter could be spared invasive biopsies, which can lead to severe side-effects.
The NHS is already reviewing whether the scans can be introduced widely.
Prostate cancer is the most common cancer in British men (...)"
"If men have high prostate specific antigen (PSA) levels in the blood, they go for a biopsy.
Twelve needles then take random samples from the whole of the prostate.
It can miss a cancer that is there, fail to spot whether it is aggressive, and cause side-effects including bleeding, serious infections and erectile dysfunction.
"Taking a random biopsy from the breast would not be accepted, but we accept that in prostate," said Dr Hashim Ahmed, a consultant and one of the researchers.
Around 100,000 to 120,000 men go through this every year in the UK."
(...)
"93% of aggressive cancers were detected by using the MRI scan to guide the biopsy compared with just 48% when the biopsy was done at random."
Sobre o Nutella (reloaded)
Sobre o Nutella (ingredientes graficamente) e um Q&A final interessante:
https://www.theguardian.com/lifeandstyle/shortcuts/2017/jan/20/is-nutella-really-that-bad-for-you
https://www.theguardian.com/lifeandstyle/shortcuts/2017/jan/20/is-nutella-really-that-bad-for-you
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